Table 1.
Test | Mean (SE) | Overall treatment effect | Simple contrast analysis | ||||||
---|---|---|---|---|---|---|---|---|---|
PLA versus 0.2 g/L | PLA versus 0.5 g/L | PLA versus 0.8 g/L | |||||||
PLA | 0.2 g/L | 0.5 g/L | 0.8 g/L | F | p | p | p | p | |
Critical Tracking Test | |||||||||
Lambda (rad/s) | 3.77 (0.12) | 3.59 (0.14) | 3.69 (0.13) | 3.46 (0.13) | 5.40 | <0.01 | <0.05 | 0.24 | <0.001 |
Divided Attention Test | |||||||||
Average error (mm) | 15.2 (0.7) | 16.0 (0.7) | 15.0 (0.7) | 17.0 (0.8) | 2.70 | 0.07 | 0.18 | 0.73 | <0.05 |
RT (ms) | 1,873 (64.0) | 1,996 (79.1) | 1,988 (62.1) | 2,082 (64.1) | 5.71 | <0.01 | <0.05 | <0.01 | 0.001 |
Psychomotor Vigilance Test | |||||||||
1/RT (ms) | 4.05 (0.1) | 3.96 (0.1) | 3.91 (0.1) | 3.75 (0.1) | 5.74 | <0.01 | 0.14 | <0.01 | 0.001 |
RT (ms) | 261 (6.6) | 268 (9.0) | 275 (9.3) | 286 (7.9) | 6.49 | <0.01 | 0.23 | 0.01 | <0.001 |
Digit Symbol Substitution Test | |||||||||
Correct responses | 99.2 (3.2) | 100.8 (2.7) | 97.8 (3.0) | 93.3 (2.2) | 11.12 | <0.001 | 0.57 | 0.49 | <0.01 |
Attention Network Test | |||||||||
Overall RT (ms) | 468 (12.5) | 470 (11.1) | 473 (13.3) | 498 (12.1) | 9.93 | <0.001 | 0.74 | 0.45 | 0.001 |
Alerting effect (ms) | 63.8 (8.2) | 53.6 (5.6) | 67.0 (8.5) | 75.7 (8.0) | 2.25 | 0.11 | 0.22 | 0.72 | 0.27 |
Orienting effect (ms) | 32.1 (4.8) | 32.4 (3.8) | 27.1 (4.4) | 31.9 (5.1) | 0.45 | 0.72 | 0.95 | 0.35 | 0.98 |
Conflict effect (ms) | 77.8 (8.4) | 80.2 (8.1) | 86.3 (8.6) | 98.9 (8.5) | 2.24 | 0.11 | 0.64 | 0.42 | 0.07 |
Concept Shifting Test | |||||||||
RT CST-A (s) | 20.1 (0.69) | 22.5 (0.85) | 20.6 (071) | 20.4 (0.88) | 3.04 | 0.05 | 0.02 | 0.47 | 0.69 |
RT CST-B (s) | 24.1 (0.77) | 23.7 (0.95) | 23.4 (0.81) | 23.6 (0.80) | 0.22 | 0.88 | 0.70 | 0.40 | 0.64 |
RT CST-C (s) | 28.1 (1.08) | 27.8 (1.19) | 26.7 (1.11) | 27.8 (1.31) | 0.39 | 0.76 | 0.79 | 0.32 | 0.86 |
Interference (CSTi) | 28.1 (4.8) | 21.3 (4.9) | 22.5 (4.8) | 27.2 (5.1) | 0.43 | 0.74 | 0.36 | 0.47 | 0.89 |
Digit Span Test | |||||||||
Forward—correct | 8.1 (0.5) | 8.6 (0.4) | 8.5 (0.4) | 7.9 (0.4) | 2.49 | 0.09 | 0.09 | 0.33 | 0.58 |
Backward—correct | 8.8 (0.4) | 8.5 (0.5) | 8.5 (0.5) | 8.0 (0.4) | 1.76 | 0.19 | 0.32 | 0.41 | <0.05 |
Balance Test | |||||||||
A95—eyes open (cm) | 0.09 (0.1) | 0.28(0.1) | 0.54 (0.1) | 1.04 (0.1) | 14.12 | <0.001 | 0.07 | 0.001 | <0.001 |
A95—eyes closed (cm) | 0.50 (0.1) | 0.64 (0.1) | 0.87 (0.1) | 1.18 (0.2) | 6.53 | <0.01 | 0.37 | 0.001 | <0.01 |
Subjective evaluations | |||||||||
Drunkenness | |||||||||
Before tests | 8.3 (2.1) | 28.8 (4.2) | 39.3 (4.5) | 51.3 (4.0) | 28.49 | <0.001 | <0.001 | <0.001 | <0.001 |
After tests | 10.0 (2.0) | 27.5 (4.0) | 34.8 (3.7) | 45.6 (4.2) | 20.77 | <0.001 | 0.001 | <0.001 | <0.001 |
Alertness | 69.3 (3.2) | 64.3 (3.6) | 65.6 (3.6) | 56.1 (4.0) | 11.86 | <0.001 | 0.09 | 0.23 | 0.001 |
Contentedness | 79.2 (2.3) | 79.5 (2.3) | 80.5 (2.5) | 81.0 (2.3) | 0.83 | 0.49 | 0.83 | 0.29 | 0.15 |
Calmness | 79.6 (2.7) | 76.3 (3.2) | 76.0 (3.4) | 77.1 (2.6) | 1.37 | 0.28 | 0.13 | 0.11 | 0.30 |
RT reaction time