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. 2014 Jan 10;231(12):2435–2447. doi: 10.1007/s00213-013-3408-y

Table 1.

Mean (SE), overall treatment effects, and contrast analyses of performance tests

Test Mean (SE) Overall treatment effect Simple contrast analysis
PLA versus 0.2 g/L PLA versus 0.5 g/L PLA versus 0.8 g/L
PLA 0.2 g/L 0.5 g/L 0.8 g/L F p p p p
Critical Tracking Test
 Lambda (rad/s) 3.77 (0.12) 3.59 (0.14) 3.69 (0.13) 3.46 (0.13) 5.40 <0.01 <0.05 0.24 <0.001
Divided Attention Test
 Average error (mm) 15.2 (0.7) 16.0 (0.7) 15.0 (0.7) 17.0 (0.8) 2.70 0.07 0.18 0.73 <0.05
 RT (ms) 1,873 (64.0) 1,996 (79.1) 1,988 (62.1) 2,082 (64.1) 5.71 <0.01 <0.05 <0.01 0.001
Psychomotor Vigilance Test
 1/RT (ms) 4.05 (0.1) 3.96 (0.1) 3.91 (0.1) 3.75 (0.1) 5.74 <0.01 0.14 <0.01 0.001
 RT (ms) 261 (6.6) 268 (9.0) 275 (9.3) 286 (7.9) 6.49 <0.01 0.23 0.01 <0.001
Digit Symbol Substitution Test
 Correct responses 99.2 (3.2) 100.8 (2.7) 97.8 (3.0) 93.3 (2.2) 11.12 <0.001 0.57 0.49 <0.01
Attention Network Test
 Overall RT (ms) 468 (12.5) 470 (11.1) 473 (13.3) 498 (12.1) 9.93 <0.001 0.74 0.45 0.001
 Alerting effect (ms) 63.8 (8.2) 53.6 (5.6) 67.0 (8.5) 75.7 (8.0) 2.25 0.11 0.22 0.72 0.27
 Orienting effect (ms) 32.1 (4.8) 32.4 (3.8) 27.1 (4.4) 31.9 (5.1) 0.45 0.72 0.95 0.35 0.98
 Conflict effect (ms) 77.8 (8.4) 80.2 (8.1) 86.3 (8.6) 98.9 (8.5) 2.24 0.11 0.64 0.42 0.07
Concept Shifting Test
 RT CST-A (s) 20.1 (0.69) 22.5 (0.85) 20.6 (071) 20.4 (0.88) 3.04 0.05 0.02 0.47 0.69
 RT CST-B (s) 24.1 (0.77) 23.7 (0.95) 23.4 (0.81) 23.6 (0.80) 0.22 0.88 0.70 0.40 0.64
 RT CST-C (s) 28.1 (1.08) 27.8 (1.19) 26.7 (1.11) 27.8 (1.31) 0.39 0.76 0.79 0.32 0.86
 Interference (CSTi) 28.1 (4.8) 21.3 (4.9) 22.5 (4.8) 27.2 (5.1) 0.43 0.74 0.36 0.47 0.89
Digit Span Test
 Forward—correct 8.1 (0.5) 8.6 (0.4) 8.5 (0.4) 7.9 (0.4) 2.49 0.09 0.09 0.33 0.58
 Backward—correct 8.8 (0.4) 8.5 (0.5) 8.5 (0.5) 8.0 (0.4) 1.76 0.19 0.32 0.41 <0.05
Balance Test
 A95—eyes open (cm) 0.09 (0.1) 0.28(0.1) 0.54 (0.1) 1.04 (0.1) 14.12 <0.001 0.07 0.001 <0.001
 A95—eyes closed (cm) 0.50 (0.1) 0.64 (0.1) 0.87 (0.1) 1.18 (0.2) 6.53 <0.01 0.37 0.001 <0.01
Subjective evaluations
 Drunkenness
  Before tests 8.3 (2.1) 28.8 (4.2) 39.3 (4.5) 51.3 (4.0) 28.49 <0.001 <0.001 <0.001 <0.001
  After tests 10.0 (2.0) 27.5 (4.0) 34.8 (3.7) 45.6 (4.2) 20.77 <0.001 0.001 <0.001 <0.001
 Alertness 69.3 (3.2) 64.3 (3.6) 65.6 (3.6) 56.1 (4.0) 11.86 <0.001 0.09 0.23 0.001
 Contentedness 79.2 (2.3) 79.5 (2.3) 80.5 (2.5) 81.0 (2.3) 0.83 0.49 0.83 0.29 0.15
 Calmness 79.6 (2.7) 76.3 (3.2) 76.0 (3.4) 77.1 (2.6) 1.37 0.28 0.13 0.11 0.30

RT reaction time