Table 3.

Neural activation during the social cognition (ToM) task assessed with the ‘Eyes’ test within the LPS > placebo contrast, paired t-test

Brain regions	MNI coordinates for LPSToM>gender > placeboToM>gender condition
	H	x	y	z	BA	t-value
Fusiform gyrus	L	−34	−24	−26		5.47*
Lingual gyrus	R	12	−84	0		3.78
Insula	R	40	−4	−6		4.15
Parahippocampal gyrus	R	24	−34	−4	27	4.22
Cingulate gyrus	L	−4	2	46	24	3.69
Medial prefrontal cortex	R	6	60	−8	10	4.01
Superior frontal gyrus	R	30	40	38		3.90
Middle temporal gyrus	R	44	−84	20	19	4.62
Middle temporal gyrus	L	−46	−84	20	39	3.82
Temporo-parietal junction	R	54	−44	22		5.26*
Superior temporal gyrus	R	60	−6	2	22	5.18*
Superior temporal gyrus	R	52	−6	4		4.51
Superior temporal gyrus	R	52	−34	16	41	3.93
Claustrum	R	34	−8	−8		3.72
Precentral gyrus	R	44	−8	36	6	3.90
Precentral gyrus	L	−50	−5	53	6	3.69
Postcentral gyrus	R	8	−52	72	7	3.86
Postcentral gyrus	L	−38	−24	46	3	4.27
Inferior parietal lobule	R	52	−44	28		4.79
Middle occipital gyrus	R	42	−82	32	19	6.62
Precuneus	R	44	−80	34		6.57*
Cuneus	R	10	−60	6	30	3.89
Cuneus	R	2	−84	16	18	4.06
Cuneus	L	−2	−82	16	18	3.78
Cuneus	L	−12	−100	2		3.79
Cuneus	L	−10	−78	20	18	3.76

H, hemisphere with activation; R, right asymmetrical activation; L, left asymmetrical activation; BA, Brodmann areas.

Paired t-test for LPS_ToM>gender > placebo_ToM>gender (n = 18). The opposite contrast revealed no significant activations. All P < 0.05 based on ROI analysis using SVC with FWE correction (*) or whole-brain statistics at P < 0.001 uncorrected.