Table 1.
Comparison between idiopathic pleuroparenchymal fibroelastosis (IPPFE) and idiopathic pulmonary fibrosis (IPF): clinical characteristics
| IPPFE (n = 6) | IPF (n = 28) | p value | |
|---|---|---|---|
| Sex, male/female |
5/1 |
26/2 |
0.452* |
| Age at biopsy, yr |
69.2 ± 3.9 |
61.4 ± 9.9 |
0.072 |
| Smoking history, current/ex/never |
0/3/3 |
13/13/2 |
0.011* |
| Pack-year of smoking |
29.3 ± 33.1 |
66.8 ± 97.4 |
0.363 |
| Detection by medical check-up, n (%) |
3 (50) |
21 (75.0) |
0.328* |
| Respiratory symptoms at biopsy, n (%) |
6 (100) |
19 (67.9) |
0.162* |
| Body mass index, kg/m2 |
17.9 ± 0.9 |
24.3 ± 2.8 |
<0.0001 |
| Clubbing of finger, n (%) |
1 (16.7) |
6 (21.4) |
0.999* |
| Fine crackles, n (%) |
3 (50) |
27 (96.4) |
0.012* |
| Pneumothorax, n (%) |
4 (66.7) |
1 (3.6) |
0.002* |
| Acute exacerbation, n (%) |
1 (16.7) |
6 (21.4) |
0.999* |
| Therapeutic intervention, n (%) |
4 (66.7) |
15 (53.6) |
0.672* |
| Period from detection of IP until acquisition of lung specimens |
73.3 ± 46.1 |
29.7 ± 34.3 |
0.012 |
| Observation period, mo |
39.8 ± 29.2 |
67.8 ± 46.7 |
0.206 |
| Death, n (%) | 3 (50.0) | 12 (42.9) | 0.999* |
Data are presented as n, mean ± SD or n (%).
Data were analyzed with Student’s t-test or *Fisher’s exact probability test.
Abbreviations: IPPFE idiopathic pleuroparenchymal fibroelastosis, IPF idiopathic pulmonary fibrosis, IP interstitial pneumonia.