Fig. 5.
A2A but not A1 receptor actions are blocked by dihydropyridines. a Time course illustrates the sequential reduction with CCPA and the reversal of current amplitude with CGS 21680. The action of the A2A-receptor agonist was blocked by 5 μM nicardipine. b Representative I-V plots taken from the time course in a as indicated by the numbers. c Box plots summarizing a sample of similar experiments (n = 10 for control; n = 6 for nicardipine, CCPA and CGS). d Time course shows that 5 μM nicardipine administered first occludes the action of high but not of low concentrations of adenosine. e Representative I-V plots taken from the time course in d as indicated by the numbers. f Box plots summarizing a sample of similar experiments (n = 12)