Figure 8.

Electrophysiological evaluation of retinal function in ashen mice. (A) Representative individual traces of dark-adapted (upper row) and light-adapted (lower row) ERGs in an ashen mouse (left column) in comparison to control mouse (right column). Flash intensities ranged from 10^–4 to 25 cd*s/m². (B) Group comparison of ashen and wild-type mice. Displayed is the dark-adapted (DA) and light-adapted (LA) b-wave amplitude vs. the logarithm of the stimulus intensity. The response distribution characteristics of the ashen mice are shown as box-and-whisker-plots featuring 5 and 95% quantiles (whiskers), 25 and 75% quartiles (box), and the median (marked by an asterisk). The 5 and 95% quantiles of the control mice, indicating the normal range, are given as solid lines, revealing that the responses of the ashen mice were within normal limits.