. Author manuscript; available in PMC: 2015 Apr 9.

Published in final edited form as: Chem Rev. 2014 Mar 3;114(7):3659–3853. doi: 10.1021/cr400327t

Table 21.

Intrinsic isotope effects for the H-atom abstraction step.

Enzyme (Substrate)	D_k (intrinsic) Primary	D_k (intrinsic) Secondary
PHM (hippuric acid)⁵⁷⁸	10.6	1.20
DβM (dopamine)^580,592	10.9	1.19