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. Author manuscript; available in PMC: 2015 Apr 9.
Published in final edited form as: Chem Rev. 2014 Mar 3;114(7):3659–3853. doi: 10.1021/cr400327t

Table 30.

Decay rates and SKIE’s of T1D WT and variants in Fet3p

T1D T1DE487D T1DE487A T1DD94E
rate of PI decay
pH=5.0		 1.8×10−3s−1 (1.6±0.1)×10−4s−1 (7.2±0.5)×10−5s−1 (3.7±0.4)×10−4s−1
rate of PI decay
pH=7.5		 2.9×10−4s−1 (5.2±0.9)×10−5s−1 (8±1)×10−5s−1 (4±1)×10−5s−1
rate enhancement 6.2× 3.1× 1× 8.0×
SKIE@low pH 0.89 2.0 ~1 2.3
pH effect on resting T2 Cu yes Yes yes no