. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Oral Maxillofac Surg Clin North Am. 2014 May;26(2):123–141. doi: 10.1016/j.coms.2014.01.001

Table 4.

Effects of tissue changes in autofluorescence

Tissue Diagnosis^*	Autofluorescence
Epithelial hyperplasia	No change
Dysplasia	Complete or partial loss
Invasive carcinoma	Complete loss
Verruciform hyperkeratosis (i.e. PVL)	No change or increase
Inflammation	Complete or partial loss
Increased vascularity or vascular tumor	Complete or partial loss
Extensive fibrosis (i.e. Submucous fibrosis)	Increased
Exogenous pigmented lesion (i.e. Amalgam tattoo)	Complete loss
Endogenous pigmented lesion (i.e. Focal melanosis)	Complete loss
Surface bacterial or fungal colonization (i.e. Hairy tongue or Candidiasis)	Altered red to orange fluorescence (porphyrin-related)

Diagnosis as confirmed by tissue biopsy