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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Metabolism. 2014 Jan 17;63(4):441–451. doi: 10.1016/j.metabol.2014.01.006

Figure 1. Regulation and roles of PGC-1α in skeletal muscle.

Figure 1

Exercise and calorie restriction induce PGC-1α expression and activation. Induction of PGC-1α affects multiple pathways and processes in the myocyte, as well as systemic physiological effects.