Table 1.
Characteristic | Healthy controls | Low Eosinophils | High Eosinophils |
---|---|---|---|
Number of subjects | 20 | 20 | 20 |
Age (years) | 27.8 (19–43) | 29.2 (20–55) | 30.5 (18–57) |
Gender: F/M | 15/5 | 14/6 | 10/10 |
Duration of asthma: >=6 months to <1 year | not applicable | 0 | 1 |
>=1 year to <5 years | 3 | 4 | |
>=5 years to <10 years | 5 | 3 | |
>=10 years to <15 years | 3 | 4 | |
>=15 years | 9 | 8 | |
Tobacco use: Former/never smoker | 0/20 | 6/14 | 6/14 |
FEV1 (% predicted) | 97.9 (81.7–119.0) | 77.1 (61.9–87.7) | 75.7 (60.0–88.9) |
Reversibility (FEV1 % change) | not applicable | 15.5 (0.6–42.3) | 15.7 (7.4–29.9) |
PC20 methacholine (mg/ml) Submucosal eosinophils (cells mm−2) |
>16 | 1.2 (0.5–2.4)(n=2) 0 (0–0.45) |
4.1 (1.2–7.0)(n=5) 39.04 (23.43–46.28) |
3.58 (0–6.20) |
Clinical data are means (ranges), cell data are medians and interquartile ranges