Table 2.
Rate of Nicotine Dependence Across Slow and Normal Metabolizers of Nicotine, Overall and by Sex and Race
| FTND | HSI | TTFC | FTND CPD | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||||||
| < 5 | ≥ 5 | χ2 | p | < 4 | ≥ 4 | χ2 | p | ≥ 6 mins | ≤ 5 mins | χ2 | p | ≤10 | 11–20 | 21–30 | > 30 | χ2 | p | |
| Overall | ||||||||||||||||||
| Slow | 34% | 66% | 1.53 | .22 | 60% | 40% | 4.64 | .03 | 63% | 37% | 0.10 | .75 | 15% | 63% | 20% | 2% | 13.3 | .004 |
| Normal | 30% | 70% | 52% | 48% | 62% | 38% | 8% | 64% | 24% | 5% | ||||||||
| Men | ||||||||||||||||||
| Slow | 41% | 59% | 5.24 | .02 | 66% | 34% | 8.42 | .004 | 69% | 31% | 0.87 | .35 | 12% | 66% | 20% | 2% | 12.6 | .006 |
| Normal | 30% | 70% | 51% | 49% | 65% | 35% | 5% | 62% | 26% | 7% | ||||||||
| Women | ||||||||||||||||||
| Slow | 24% | 76% | 1.09 | .30 | 52% | 48% | 0.03 | .86 | 53% | 47% | 0.91 | .34 | 19% | 60% | 20% | 1% | 5.2 | .16 |
| Normal | 30% | 70% | 53% | 47% | 59% | 41% | 11% | 66% | 21% | 2% | ||||||||
| Caucasian | ||||||||||||||||||
| Slow | 37% | 63% | 0.79 | .38 | 60% | 40% | 2.05 | .15 | 69% | 31% | 0.09 | .76 | 11% | 57% | 31% | 1% | 9.9 | .02 |
| Normal | 32% | 68% | 52% | 43% | 67% | 33% | 4% | 62% | 29% | 5% | ||||||||
| African American | ||||||||||||||||||
| Slow | 33% | 67% | 2.64 | .10 | 61% | 39% | 1.99 | .16 | 59% | 42% | 3.98 | .05 | 18% | 68% | 12% | 2% | 0.3 | .95 |
| Normal | 24% | 76% | 53% | 47% | 47% | 53% | 17% | 69% | 11% | 3% | ||||||||
Note. FTND = Fagerström Test for Nicotine Dependence; HSI = Heaviness of Smoking Index; TTFC = Time to first cigarette; CPD Cigarettes per day.