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Effects of 17β estradiol, ZYC-26 and ZYC-23 on TUNEL positive cell number in the cortex in mice subjected to blunt TBI. 17β estradiol, ZYC-26 and ZYC-23 were administered intravenously at a dose of 100 µg/kg, 30 min before contusion and animals were sampled 24 hours later. # indicates a p<0.05 vs. Sham; * indicates a p<0.05 vs. OVX + Placebo and OVX + ZYC-23.
