Table 1. Characteristics of RNA elements that are riboswitch candidates in B. subtilis.
RNA element | Num | Distribution | Term | Reg | Gene functions |
---|---|---|---|---|---|
glmS | 18 | B/C, Fus | — | — | GlcN6P synthetase |
gcvT | 27 | B/C, α, β, γ, Act | + | + | Glycine cleavage system, Na+/alanine symporter |
ydaO/yuaA | 15 | B/C, Act | + | — | K+ transporter, membrane metalloproteases |
ykkC/yxkD | 19 | B/C, Cya, α, β, γ, ε | + | + | Multidrug resistance, N/S/B transport |
ykoK | 21 | B/C, β, γ, Act | + | — | Divalent metal transporters |
yybP/ykoY | 56 | B/C, Cya, α, β, γ, Act | + | + | Cation transport ATPase |
Motifs are named for the initial gene of each downstream operon in B. subtilis. The number of sequence representatives (Num), evolutionary distribution, presence of an intrinsic terminator before downstream start codons in Gram-positive bacteria (Term), and predicted or known effect of metabolite binding by the RNA element on gene expression (Reg) are shown for each element. Bacterial classification abbreviations: B/C, Bacillus/Clostridium; α, α-proteobacteria; β, β-proteobacteria; γ, γ-proteobacteria; ε, ε-proteobacteria; Cya, cyanobacteria; Fus, fusobacteria; Act, actinobacteria. N/S/B, nitrate/sulfonate/bicarbonate.