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. 2014 May 12;111(21):7831–7836. doi: 10.1073/pnas.1401938111

Fig. 5.

Fig. 5.

Or67d levels are reduced in dATP8B mutant cilia. (A) Example of GFP-tagged Or67 expressed in wild-type dATP8B background (genotype, w: UAS GFPOr67d ; Or67dGAL4 /+). (B) Typical example of GFP-tagged Or67d in the dATP8B mutant background (genotype w ; UAS GFPOr67d ; Or67dGAL4, dATP8B5/dATP8B5). (C) Quantification of cilia to cell body ratio GFP-tagged Or67d in wild type and dATP8B mutants. Genotypes are significantly different at P < 0.01 by Student’s 2-tailed t test. n = 20 for each bar. (D) Quantification of cilia to cell body signal ratio for Orco in Or67d neurons. Error bars represent SEM. n = 20 for each. (E) Bovine ATP8A2 expressed under control of the Or67d promoter in the dATP8B5 mutant background localizes to the proximal dendrites of the Or67d neurons (genotype w ; UAS ATP8A2 ; Or67dGAL4, dATP8B5/dATP8B5). (F) Graph depicts the cVA dose–response curves for dATP8B5 mutants expressing bovine ATP8A2 compared with wild-type controls. n ≥ 10 for each time point.