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. 2014 May 12;111(21):7747–7752. doi: 10.1073/pnas.1400139111

Fig. 8.

Fig. 8.

DHX29 binds to nucleic acids, RIG-I, and MAVS via the helicase 1 domain. Cell lysates of 293T cells overexpressed with various deletion mutants of HA-DHX29 (A) mixed with biotinylated poly I:C or poly dAdT:dAdT were immunoprecipitated with NeutrAvidin beads (B). Cell lysates overexpressed with deletion mutants of HA-DHX29 with Myc–RIG-I-ΔC or with Myc-MAVS were immunoprecipitated with anti-Myc (B) or anti-HA beads (C). The immunoprecipitated elutes (IP) were detected by Western blot analysis with anti-HA (B) or anti-Myc (C) antibodies. Data are representative of at least three independent experiments.