Figure 1.
Survival rate of Nude BALB/c mice treated with [Pt(O,O'-acac)(γ-acac)(DMS)] (a) and with cisplatin (b). (c) Body weight variations observed after 10 days from the intravenous administration of [Pt(O,O'-acac)(γ-acac)(DMS)] and cisplatin. Results represent the average weight of the six animals per group. (d) Tissue distribution of [Pt(O,O'-acac)(γ-acac)(DMS)] and cisplatin in female mice, after 30 days from the intravenous administration. Statistical analyses were performed using one-way ANOVA with a Tukey post hoc test, P<0.05 (compared with control)