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. 2014 Jan 23;5(1):e1019. doi: 10.1038/cddis.2013.559

Figure 2.

Figure 2

JNK and caspase-3 pathways were activated in the postsynaptic compartment in TgCRND8 mice. (a and b) Western blot and relative quantification showing P-JNK and JNK levels in the TIF fraction of 2-months-old Wt and TgCRND8 mice. P-JNK/JNK ratio was increased by 1.87-fold in TgCRND8 mice if compared with the age-matched Wt mice (Student's t-test, *P<0.05, n=6). (c and d) Western blot and relative quantification showing P-JNK and JNK levels in the TIF fraction of 9-months-old Wt and TgCRND8 mice. P-JNK/JNK ratio was increased by 2.25-fold in TgCRND8 mice if compared with the age-matched Wt mice (Student's t-test, **P<0.01, n=6)