Table 3. MicroRNAs in HNSCC.
| MicroRNA | Targets | Function | References |
|---|---|---|---|
| Upregulated | |||
| miR-21 | PTEN, PCDC4 | Cell cycle progression, metastasis | 129 |
| miR-106b | p21 | Cell cycle progression | 130 |
| miR-205 | PTEN | Prognostic marker, metastasis | 131,132 |
| miR-181 | not reported in HNSCC | Prognostic factor, metastasis | 135 |
| miR-211 | not reported in HNSCC | Prognostic factor, metastasis | 134 |
| Downregulated | |||
| let-7 | KRAS | Prognostic marker, metastasis | 131,136 |
| miR-133a/b | PKM2, ARPC5 | Cancer metabolism | 137,138 |
| miR-200a | ZEB1, ZEB2 | EMT, metastasis | 139 |