Table 4.
Comparison of the IBD cohorts with the control group in terms of smoking and comorbidities
| Cohort |
|||
|---|---|---|---|
| Factor | Controls (n = 355) | CD (n = 190) | UC (n = 148) |
| Smoking at diagnosis | 69 (19) | 80 (42)** | 53 (36)** |
| Daily number of cigarettes at Dx | 2.3 ± 6.0 | 4.3 ± 6.2** | 4.1 ± 7.2* |
| Duration of smoking at Dx (years) | 4.1 ± 8.6 | 2.5 ± 5.0 | 3.4 ± 6.9 |
| Appendectomy | 25 (7.0) | 41 (21.6)** | 10 (6.8) |
| Tonsillectomy | 64 (18) | 35 (18) | 24 (16) |
| Depression | 12 (3) | 13 (7) | 13 (9)* |
| Eczema | 71 (20) | 41 (22) | 30 (20) |
| Allergic rhinoconjunctivitis | 66 (19) | 35 (18) | 24 (16% |
| Allergy: self reported | 112 (32) | 67 (35) | 51 (35) |
| Pollen | 51 (14) | 34 (18) | 24 (16) |
| Dust mite | 34 (10) | 18 (10) | 15 (10) |
| Food | 21 (6) | 15 (8) | 10 (7) |
Values are mean ± SD or n (%). *Statistical difference vs. controls (p < 0.05). **Statistical difference vs. controls (p < 0.001). CD, Crohn’s disease; Dx, diagnosis; UC, ulcerative colitis.