Table 3.

Risk of BO on different subgroups

Subgroups	Non-Smokers		Any time smokers				Current Smokers				Past Smokers
	N	BO(%)	N	BO(%)	p value	OR	N	BO(%)	p value	OR	N	BO(%)	p value	OR
Age <60Yr	128	3 (2.3)	447	66 (14.8)	<0.001	7.2 (2.2–23.4)	259	43 (16.6)	<0.01	8.3 (2.5–27.3)	188	23 (12.2)	0.001	5.8 (1.7–19.8)
Age ≥60 Yr	89	9 (10.1)	331	61 (18.4)	0.07	2.0 (0.95–4.2)	76	17 (22.4)	0.03	2.5 (1.1–6.1)	255	44 (17.3)	0.12	1.8 (0.9–3.0)
Male Gender	207	12 (8.3)	771	132 (17.1)	<0.01	3.4 (1.8–6.2)	330	59 (17.9)	<0.01	3.5 (1.9–6.8)	441	73 (16.6)	<0.01	3.2 (1.7–6.1)
Female Gender	22	0 (0)	49	7 (14.3)	0.09	NC	22	4 (18.2)	0.1	NC	27	3 (6.1)	0.24	NC
Caucasian	193	12 (6.2)	680	131 (19.3)	<0.01	3.6 (1.9–6.6)	286	56 (19.6)	<0.01	3.7 (1.9–7.0)	394	75 (19.0)	<0.01	3.5 (1.8–6.7)
Non-Caucasian	35	0 (0)	135	7 (5.2)	0.34	NC	64	6 (9.4)	0.09	NC	71	1 (1.4)	0.99	NC
BMI <30	128	9 (7.0)	486	90 (18.5)	<0.01	3.0 (1.5–6.1)	227	44 (19.4)	<0.01	3.2 (1.5–6.8)	259	46 (17.8)	<0.01	2.9 (1.4–6.0)
BMI ≥30	100	3 (3.0)	332	49 (14.8)	<0.01	5.6 (1.7–18.3)	122	17 (13.9)	<0.01	5.2 (1.5–18.4)	210	32 (15.2)	<0.01	5.8 (1.7–19.5)
HB ≥5 Yr	96	5 (5.2)	460	88 (19.2)	<0.01	4.3 (1.7–10.9)	211	45 (21.3)	<0.01	4.9 (1.9–12.9)	249	43 (17.2)	<0.01	3.8 (1.5–9.9)
HB <5 yr	117	6 (5.1)	307	37 (12.1)	0.04	2.5 (1.1–6.2)	129	14 (10.9)	0.11	2.2 (0.83–6.0)	177	23 (13.0)	0.02	2.7 (1.1–7.0)
Presence of HH	104	12 (11.5)	413	99 (24)	<0.01	2.4 (1.2–4.5)	167	42 (25.1)	<0.01	2.5 (1.3–5.2)	246	57 (23.2)	0.01	2.3 (1.2–4.5)
Absence of HH	122	1 (0.8)	407	43 (10.6)	<0.01	14.2 (1.9–104.9)	183	21 (11.5)	<0.01	15.6 (2.0–118.2)	224	22 (9.8)	<0.01	13.1 (1.7–99.0)

HB: heartburn; HH: hiatal hernia; BMI: body mass index; BO: Barrett’s oesophagus; OR: odds ratio; CI: confidence interval; NC: not calculable.