Table 6.

Performance of the calprotectin assays for detecting disease activity in ulcerative colitis

Assay	Cut off (µg/g)	Mayo 1 (n=7) vs. Mayo 0 (n=7, except Calprest/Calfast n=6)						Mayo 2–3 (n=8) vs. Mayo 0 (n=7, except Calprest/Calfast n=6)
		Sensitivity	Specificity	NPV	PPV	LR+	LR–	Sensitivity	Specificity	NPV	PPV	LR+	LR–
Calprolab	86	71	86	75	83	5	0.33	100	86	100	89	6.0	0
QB BM	129	71	86	75	83	5	0.33	100	86	100	89	6.0	0
Phadia	31	86	86	86	86	6	0.17	100	86	100	89	6.0	0
Calfast	50	100	67	100	88	3	0	100	67	100	80	3.0	0
Calprest	56	86	83	83	86	5	0.17	100	83	100	89	6.0	0
Certest	50	100	57	100	70	2.3	0	100	57	100	73	2.3	0
200	57	86	67	80	4.0	0.5	75	86	75	86	5	0.3

LR+, positive likelihood ratio; LR–, negative likelihood ratio; Mayo, Mayo endoscopic subscore; NPV, negative predictive value; PPV, positive predictive value; QB BM, Quantum Blue Bühlmann.