Fig. 2.

The summed contribution from components 3 and 8 of the Blocks9 Dirichlet mixture for the multiple sequence subalignments corresponding to the 13 human tumor suppressor proteins. These plots are analogous to those in Fig. 1B (see Methods for details). Subalignments (gray vertical lines; sequence identities are listed in Table 2) were selected either by visual inspection or with an edge-detection algorithm (see Methods). No abrupt rise is seen for ARF (7), likely because all sequences are from mammals.