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Progression-free survival (PFS) by number of comorbidities. Kaplan-Meier estimates for (A) all subjects, (B) CLL4 subjects, (C) CLL5 subjects. Hazard ratios (D) of predictive factors identified by multivariate analysis (boxes represent the hazard ratios, lines the 95% confidence intervals). FC: fludarabine+cyclophosphamide; TK: thymidine kinase; β2M: β2 microglobulin.
