Table 2. Laboratory Parameters at Baseline and Follow-up and Medication Exposure over the Study Interval.
| Non-Dialysis | Dialysis | |||||
|---|---|---|---|---|---|---|
| Baseline | Follow-Up | p value for change | Baseline | Follow-up | p value for change | |
| Laboratory Results | ||||||
| eGFR ml/min/1.73m2 | 41 ± 14 | 37 ± 16 | < 0.001 | |||
| iPTH (pg/ml) | 49 (27,84) | 61 (30,119) | < 0.01 | 146 (85,479) | 183 (62,504) | 0.85 |
| Phosphorus (mg/dL) | 4.4 (3.8,5.0) | 4.5 (4.0,5.5) | < 0.01 | 5.4 (3.9,6.5) | 6.5 (4.9,7.7) | < 0.05 |
| Corrected Calcium (mg/dL) | 9.6 (9.3,10.0) | 9.5 (9.2,10.0) | 0.67 | 9.4 (8.6,9.6) | 9.5 (8.9,10.1) | 0.16 |
| Bicarbonate (mmol/L) | 24 ± 3 | 24 ± 3 | 0.56 | 24 ± 4 | 25 ± 5 | 0.52 |
| Concurrent Medications, n (%) | ||||||
| Calcitriol | 34 (44) | 25 (96) | ||||
| Growth Hormone | 7 (9) | 2 (8) | ||||
| Calcineurin Inhibitor | 0 | 9 (33) | ||||
| Glucocorticoid | 4 (5) | 8 (31) | ||||
| Phosphate Binder | 25 (32) | 26 (100) | ||||
Results are presented as mean ± SD if normal distribution or as median and (interquartile range IQR)
These results are limited to those who have baseline and follow-up results for each parameter.
Calcium was corrected for those with an albumin ≤ 3.5 using Calcium + [0.8*(4.0 − albumin)]
Phosphate binders include both calcium and non-calcium contanining.