Table 2.

Optimization of ArM catalyzed oxidation^a

Entry	Solvent	Oxidant	Convb. (%)
1	Tris (25mM, 7.0), 20%ACN	Oxone, 10eq	0
2	NaPi (100mM, 7.0), 20%ACN	Oxone, 10eq	77
3	NaPi (100mM, 7.0), 20%ACN	AcOOH, 10eq	85
4	NaPi (100mM, 7.0), 20%ACN	AcOOH, 2.5eq	83
5	NaPi (100mM, 7.0), 20%ACN	AcOOH, 2eq	76
6	NaPi (100mM, 7.0), 30%ACN	AcOOH, 2.5eq	12e
7	NaPi (100mM, 7.0), 10% ACN	AcOOH, 2.5eq	91
8	NaPi (100mM, 7.0)	AcOOH, 2.5eq	24
9c	NaPi (100mM, 7.0), 10% ACN	AcOOH, 2.5eq	45e
10d	NaPi (100mM, 7.0), 10% ACN	AcOOH, 2.5eq	58

^aReaction conditions: 1 mM substrate, 5% ArM, 4 °C, overnight in dark.

^bDetermined by GC analysis of DCM extract.

^cReaction conducted at room temperature

^d2.5% ArM loading used.

^eProtein precipitation was observed.