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. Author manuscript; available in PMC: 2014 Nov 15.
Published in final edited form as: J Immunol. 2013 Oct 7;191(10):5036–5043. doi: 10.4049/jimmunol.1301132

Figure 2.

Figure 2

SOCS3-deficient CD4+ T cells promote the expansion of IL-10-producing cells. Naïve CD4+ T cells isolated from WT and CD4-SOCS3KO mice were stimulated with anti-CD3/CD28 for four days under Th0 or Th17 polarizing condition and then analyzed for cytokine expression by the intracellular cytokine staining assay (A) or for cytokine secretion by ELISA (B). Numbers in quadrants (A) indicate percent of T cells expressing IL-2, IL-10, IL-17 or IFN-γ. Results are representative of at least three independent experiments.