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. Author manuscript; available in PMC: 2014 Jun 2.
Published in final edited form as: Phys Chem Chem Phys. 2013 Aug 14;15(30):12558–12571. doi: 10.1039/c3cp44542a

Fig. 1.

Fig. 1

Aggregation of human amylin is not affected by catalytically produced H2O2. 20 μM of human amylin (hA) and rat amylin (rA) were incubated in phosphate buffer, in the absence or in presence of catalase, for 24–72 h and the extent of H2O2 accumulation (A) and amylin-aggregation (B) quantified using Amplex-Red H2O2 and Th-T-aggregation fluorescent assays, respectively. (A) Stimulatory effect of human and rat amylin on accumulation of peroxide in solution is shown. (B) Catalase had no significant effect on the aggregation of human amylin (P > 0.05, n = 6). Significance established at ***P < 0.001, hA vs. hA + catalase, n = 6, ANOVA followed by Newman–Keul post hoc test.