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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Angew Chem Int Ed Engl. 2013 Dec 11;53(4):1140–1143. doi: 10.1002/anie.201308607

Figure 2.

Figure 2

Series of HPLC traces showing the extent of conversion of compound 1 (40 μM) to EP-2104R after 15 minutes under four different reaction conditions: untreated (no enzyme or DTT added); with PDI (4 mg/L); with DTT (40 μM); and with both PDI (4 mg/L) and DTT (40 μM).