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. 2014 Apr 21;42(10):6421–6435. doi: 10.1093/nar/gku280

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© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Chromatin organization at and around the tDNA tandem repeat. Image represents a 90-kb window covering 161,368,001–161,458,000 of human chromosome 1 generated from build GRCh37/hg19. Image adapted from the UCSC genome browser (26). The location of the VNTR is indicated at top by the right-facing black arrows. The location of tRNA genes and LTR elements is indicated immediately below this. Data from chromatin immunoprecipitation coupled with massively paralleled DNA sequencing is indicated to the left for CTCF, H3K4me3, H3K9me3, H3K27me3 and the input control (44). Data are shown for LCL GM12878, hESC cell line H1, human umbilical vein endothelial cells (HUVEC), human mammary epithelial cells (HMEC) and normal human epidermal keratinocytes (NHEK) as indicated to the left of each track. Each track has maximum vertical viewing range of 250 reads.