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. 2014 Apr 19;42(10):6603–6615. doi: 10.1093/nar/gku286

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© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Crosslink site profiles of Trypanosoma brucei U1C and U1-70K on the poly(A) polymerase (PAP) pre-mRNA. The numbers of random-barcode-filtered iCLIP tags for U1C and U1-70K are plotted on the Y-axis with the corresponding crosslink sites. Shown are the exon–intron–exon region of the PAP pre-mRNA (top) and detailed information on the absolute number of CLIP tags at nucleotide resolution for the 5′ splice site region (bottom; U1C above, U1-70K below the sequence); the arrow marks the 5′ splice site (5′ ss).