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. 2014 Apr 25;42(10):6630–6644. doi: 10.1093/nar/gku290

Table 2.

Association (ka) and dissociation (kd) rates and dissociation constants (KD) determined by SPR spectroscopy; n. d.: not determined due to too weak interactions

Ligand Analyte ka (M−1s−1) x 106 kd (s−1) x 10−3 KD (nM) χ2
ΔNucleolin ARPC2 GQ 8.7 5.1 0.6 0.96
ARPC2 mut 0.5 41.4 83 1.61
MMP16 GQ 0.92 1.9 2 0.79
MMP16 mut 6 3.6 0.6 0.94
U2AF65 ARPC2 GQ 1.1 1.2 1 0.9
ARPC2 mut n. d.
MMP16 GQ 1.6 8.1 5 0.73
MMP16 mut n. d.