TABLE 3.
Pathologic and FISH Results on the Salivary Gland Myoepithelial Tumors Included in the Control Group.
| ME | Diagnosis | Location | PLAG1 | HMGA2 | FGFR1 |
|---|---|---|---|---|---|
| 36 | ME carcinoma ex-PA | parotid | rearrangeda | ND | normal |
| 37 | ME carcinoma ex-PA | parotid | rearrangeda | ND | normal |
| 38 | ME carcinoma ex-PA | parotid | rearranged & C'amplified | ND | rearranged & C'amplified |
| 39 | ME carcinoma ex-PA | parotid | rearranged & amplified | ND | rearranged & amplified |
| 40 | ME carcinoma ex-PA | parotid | rearranged & C'amplified | Normal | rearranged & C'amplified |
| 41 | ME carcinoma ex-PA | parotid | rearranged & C'amplified | ND | rearranged & C'amplified |
| 42 | ME carcinoma ex-PA | parotid | normal | rearranged & C'amplifiedb | ND |
| 43 | ME carcinoma ex-PA | parotid | normal | rearranged & C'amplified | ND |
| 44 | ME carcinoma ex-PA | floor of mouth | normal | Normal | ND |
| 45 | ME carcinoma | parotid | normal | Normal | ND |
| 46 | ME carcinoma | submand | normal | Normal | ND |
| 47 | ME carcinoma | tongue | normal | Normal | ND |
ME, myoepithelial, PA, pleomorphic adenoma; submand, submandibular; ND, not done;
a
rearrangement present in both PA and ME carcinoma components (also negative for LIFR and CTNNB1 gene rearrangements); C'amplified, centromeric portion is amplified, while telomeric part is not;
b
HMGA2 rearrangement and C'amplification noted only in the ME-carcinoma, but not in the PA component.