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. Author manuscript; available in PMC: 2014 Jun 2.
Published in final edited form as: Arthritis Rheum. 2013 Jun;65(6):1541–1546. doi: 10.1002/art.37926

Table 3.

Relationship between BMD change and ANNUAL change in cartilage outcomes

VOLUME (%) ** THICKNESS (mm)
Estimate(SE) p Femoral cartilage** Tibial cartilage**
Estimate (SE) p Estimate (SE) p
BMD change per year per 0.1g/cm2 1.29 (0.54) 0.02 0.019 (0.009) 0.04 0.021 (0.012) 0.08
BMD change per year per 0.1g/cm2 * 1.25 (0.54) 0.02 0.019 (0.010) 0.06 0.028 (0.012) 0.03
BMD change* 0.02 0.11 0.03
 Gain −0.38 (0.64) 0.55 −0.007(0.012) 0.53 −0.013(0.029) 0.37
 Loss −1.02 (0.36) 0.005 −0.014 (0.007) 0.04 −0.021(0.008) 0.009
 No change reference reference reference

A 0.1-unit change is reported because 1unit change in BMD is not clinically possible.

*

Adjusted for age, gender, BMI, malalignment status, vitamin D treatment, bisphosphonate use.

**

N=124 for volume, 119 for femoral cartilage thickness, 123 for tibial cartilage thickness