Table 3.

Relationship between BMD change and ANNUAL change in cartilage outcomes

	VOLUME (%) **		THICKNESS (mm)
	Estimate(SE)	p	Femoral cartilage**		Tibial cartilage**
			Estimate (SE)	p	Estimate (SE)	p
BMD change per year per 0.1g/cm2 †	1.29 (0.54)	0.02	0.019 (0.009)	0.04	0.021 (0.012)	0.08
BMD change per year per 0.1g/cm2 †*	1.25 (0.54)	0.02	0.019 (0.010)	0.06	0.028 (0.012)	0.03
BMD change*		0.02		0.11		0.03
Gain	−0.38 (0.64)	0.55	−0.007(0.012)	0.53	−0.013(0.029)	0.37
Loss	−1.02 (0.36)	0.005	−0.014 (0.007)	0.04	−0.021(0.008)	0.009
No change	reference		reference		reference

^†A 0.1-unit change is reported because 1unit change in BMD is not clinically possible.

^*Adjusted for age, gender, BMI, malalignment status, vitamin D treatment, bisphosphonate use.

^**N=124 for volume, 119 for femoral cartilage thickness, 123 for tibial cartilage thickness