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| Position | FR mutation | FL mutation | ||
| Hydrophobic | Hydrophilic | Hydrophobic | Hydrophilic | |
| Val25 | 124 | 11 | 0 | 0 |
| Val27 | 55 | 0 | 0 | 6 |
| Ile29 | 44 | 0 | 4 | 28 |
| Tyr41 | 24 | 0 | 0 | 42 |
| Met111 | 159 | 7 | 0 | 17 |
| Met113 | 162 | 97 | 0 | 0 |
| Tyr118 | 7 | 12 | 0 | 5 |
| Val120 | 18 | 0 | 0 | 36 |
| Ile122 | 18 | 67 | 0 | 15 |
| Total | 611 | 194 | 4 | 149 |
