Table 4. Mutation frequency of amino acid residues involved in hydrophobic interaction with FMN.

Position	FR mutations	FL mutations	Positional effect value
Val28	27	45	0.625
Tyr30	53	10	0.159
Phe46	67	31	0.316
Ile78	30	48	0.615
Leu82	197	22	0.101
Ile92	112	40	0.263
Leu65	7	55	0.875
Leu106	0	47	1
Ile108	0	54	1