TABLE 1.
Patient characteristics (N = 146)
| Characteristic | N (% of patients with available data) |
|||
|---|---|---|---|---|
| Group A, no therapy (n = 33) |
Group B, CT (n = 45) |
Group C, CRT (n = 68) |
p value | |
| Age (years) | ||||
| <70 | 22 (69) | 22 (49) | 36 (53) | 0.12 |
| ≥70 | 10 (31) | 23 (51) | 32 (47) | |
| Median (range) | 70 (45–85) | 66 (37–85) | 64 (30–85) | 0.02 |
| Sex | ||||
| Male | 10 (30) | 22 (50) | 32 (47) | 0.09 |
| Female | 23 (70) | 22 (50) | 36 (53) | |
| Not available | 0 | 1 | 0 | |
| Adjuvant Chemotherapy | NA | |||
| Gemcitabine-based | 26 (87) | 10 (22) | NA | |
| Fluoropyrimidine | 4 (13) | 35 (78) | ||
| Not available | 15 (33) | 23 (34) | ||
| Tumor locationa | ||||
| Head | 29 (88) | 41 (91) | 54 (80) | 0.29 |
| Body/tail | 4 (12) | 4 (9) | 13 (20) | |
| Not available | 0 (0) | 0 | 1 (2) | |
| Tumor differentiation | ||||
| Well-moderate | 13 (59) | 39 (73) | 30 (56) | 0.25 |
| Poor | 9 (41) | 11 (27) | 24 (44) | |
| Not available | 11 | 5 | 14 | |
| Tumor size (cm) | ||||
| <3 | 22 (67) | 30 (67) | 49 (72) | 0.79 |
| ≥3 | 11 (33) | 15 (33) | 19 (28) | |
| Lymph nodes | ||||
| Positive (N1) | 19 (63) | 25 (61) | 36 (57) | 0.87 |
| Negative (N0) | 11 (37) | 16 (39) | 27 (43) | |
| Not available | 3 | 4 | 5 | |
| Resection margins | ||||
| R0 | 25 (78) | 36 (84) | 47 (71) | 0.32 |
| R1 | 7 (22) | 7 (16) | 19 (29) | |
| Not available | 1 | 2 | 2 | |
Bold value is statistically significant
a
Within the pancreas
R0 resection negative margins,
R1 resection microscopically positive