TABLE 2.

Clinical outcomes according to treatment received

Variable	mOS (m)	95 % CI	p value
Any adjuvant therapy	16.4	14–21	0.0007
No adjuvant therapy	6.3	1.5–10.1
Type of adjuvant therapy
CT	21.5	13.4–24.6	0.76
CRT	16.8	13.9–23.1
Lymph node statusa
Negative	24	19.8–34.2	0.0003
Positive	13.8	10.9–15.2
Resection margin status
Negative (R0)	16.6	13.4–20.1	0.36
Positive (R1)ab	16.4	13.8–23.6
Tumor size (cm)
<3	16.4	12.1–21	0.0924
≥3	16.8	13.7–24
Tumor differentiation
Well-moderate	15.2	8.7–25.6	0.54
Poor	16.4	13.9–23
Sex
Male	17.1	13.9–24.3	0.55
Female	16.4	12.2–23.1
Age (years)
<70	20.4	13.7–29.9	0.0514
≥70	15.2	13.6–18.3

Bold values are statistically significant

^aIn patients receiving adjuvant therapy

^bMicroscopically positive