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. 2014 Jun 2;9(6):e94944. doi: 10.1371/journal.pone.0094944

Table 1. Relevant clinical and other variables of study participants.

Controls (n = 54) Cases (n = 26) P
Male, n [%] 33 [61.1] 20 [76.9] 0.210
Age of PD onset, mean [SD] Y 65.2 [9.8] 67.1 [10.4] 0.334
Age (at time of systemic inflammation), mean [SD] Y 75.8 [7.0] 76.0 [9.1] 0.471
PD duration, mean [SD] Y 10.7 [6.4] 8.9 [3.5] 0.431
Modified H–Y stage, n [%] 2 7 [13.0] 0 [0.0] 0.151
2.5–3 27 [50.0] 14 [53.8]
4 20 [37.0] 12 [46.2]
UPDRS-III score, mean [SD], n 26.5 [12.4], 8 35.4 [9.2], 8 0.169
Dementia, n [%] 29 [53.7] 17 [65.4] 0.347
MMSE score, mean [SD], n 24.3 [4.3], 17 20.8 [6.0], 8 0.160
History of psychosis, n [%] 32 [59.3] 22 [84.6] 0.040
Initial symptoms, non-tremor n [%] 36 [66.7] 22 [84.6] 0.114
Symptomatic orthostatic hypotension, n [%] 12 [22.2] 10 [38.5] 0.181
LED, median [range] mg/day 600 [0–1673] 481 [300–898] 0.164
Use of dopamine agonists, n [%] 20 [37.0] 4 [15.4] 0.068
Use of central anticholinergic drugs, n [%] 4 [7.4] 1 [3.8] 1.000
Delirium, n [%] 10 [18.5] 21 [80.8] <0.001
Peak body temperature, mean [SD]°C 37.8 [0.8] 38.7 [0.8] <0.001
Peak leukocyte count, mean [SD]×103/µl 11.6 [2.9] 12.4 [3.6] 0.345
Peak plasma CRP concentration, mean [SD] mg/dl 8.5 [5.9] 11.5 [6.9] 0.057
Duration of leukocytosis, n [%] 1–3 days 31 [58.5] 7 [26.9] <0.001
4–8 days 21 [39.6] 6 [23.1]
9–34 days 1 [1.9] 13 [50.0]