Table 2. Number of GO annotations and KEGG pathways enriched by six pathway enrichment tools for gene lists with allelic SNP p-value cut-offs 0.005 and 0.01.

	SNP p-value cut-off 0.005				SNP p-value cut-off 0.01
	within a gene		gene locus ±20 kb		within a gene		gene locus ±20 kb
Tool name	No. of GO Annotations	No. of KEGG pathways	No. of GO Annotations	No. of KEGG pathways	No. of GO Annotations	No. of KEGG pathways	No. of GO Annotations	No. of KEGG pathways
ConsensusPathDB	159	16	170	14	161	25	176	21
DAVID	32	0	15	0	22	5	4	1
FatiGO	7	0	5	0	5	0	4	0
GATHER	20	3	10	2	33	5	23	4
GeneCodis	133	11	172	15	223	29	278	26
WebGestalt	50	15	24	17	77	37	52	37

Pathway enrichment p-value cut-off: 0.05.