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. 2014 Jun 2;9(6):e98902. doi: 10.1371/journal.pone.0098902

Figure 1. Effect of c-Ski on oxLDL- or PDGF-induced autophagy in A10 cells.

Figure 1

c-Ski in rat A10 cells was overexpressed by Adc-Ski transfection. A10 cells were infected with Adc-Ski followed by stimulation with 40 µg/ml oxLDL or 20 ng/ml PDGF for 24 h. As a marker of autophagy, the abundance of LC3 was detected by Western blotting. (A) Effect of c-Ski on oxLDL- or PDGF-induced LC3 expression. (B) Effect of c-Ski on oxLDL- or PDGF-induced Atg5 expression. β-actin served as a control. Bar graphs represent data in mean±SEM based on 3 experiments, *: P<0.01 when compared with the control group; #: P<0.01 when compared with the oxLDL-treated group; &: P<0.01 when compared with the PDGF-treated group.