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. 2014 Jun 2;9(6):e98785. doi: 10.1371/journal.pone.0098785

Figure 2. Fully immature DENV-2 particles exhibit basic infectivity on immature dendritic cells.

Figure 2

imDCs were infected with MOG 1000 of standard (std) or immature DENV-2. Supernatant was harvested 43 hpi and analyzed. (A) DENV-2 infectivity on imDCs. (B) Role of DC-SIGN on immature DENV-2 infectivity in imDCs as tested by DC-SIGN blockage. Limit of detection is 18 PFU/ml. Data are expressed as means of at least two independent experiments performed in triplicate; error bars represent standard error of the mean (SEM). N.d. denotes for “not detectable”. Levels of significance (Mann Whitney U test) are presented as **  =  p<0.01.