Table 2.

Effects of treatment group assignment on retention and heroin use outcomes (N=126)*

	Buprenorphine n=44	Naltrexone n=43	Placebo n=39	Significance level of statistical comparisons
	Mean (95% CI)	Mean (95% CI)	Mean (95% CI)	Linear contrast	Bup vs. Placebo	Bup vs. Ntx	Ntx vs. Placebo
Days in treatment	117 (102–132)	84 (64–103)	70 (54–87)	<0.001	<0.001	<0.025	0.516
Days in treatment without heroin use	51 (33–68)	24 (11–37)	18 (8–28)	<0.001	<0.05	<0.025	0.800
Days in treatment without heroin relapse	79 (61–98)	64 (44–84)	39 (25–53)	<0.01	<0.01	0.422	0.121
Maximum consecutive days abstinent	59 (43–76)	42 (28–57)	24 (13–35)	<0.001	<0.01	0.192	0.180