Table 3.
Effects of treatment group assignment on AIDS Risk Behaviors (N=126)
Buprenorphine | Naltrexone | Placebo | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | 3-month | 6-month | Baseline | 3-month | 6-month | Baseline | 3-month | 6-month | Time effect | Medication effect | Interaction | |
n=41 | n=42 | n=36 | n=42 | n=30 | n=29 | n=39 | n=29 | n=23 | p | p | p | |
ARI total score Mean (95%CI) | 56.5(48.0–64.9) | 47.3(41.7–53.0) | 53.7(44.1–63.4) | 46.4(37.9–54.0) | 43.7(36. 7–50.6) | 43.1(33. 5–52.7) | 57.0(46.7–67.1) | 47.4(39.5–55.3) | 43.6(34.9–52.4) | <0.01 | 0.138 | 0.321 |
ARI drug risks subscore Mean (95% CI) | 38.9(32.7–45.1) | 23.1(19.3–26.8) | 25.0(20.2–29.8) | 30.4(24.0–36.8) | 22.5(18.3–26.8) | 21.8(16.5–27.1) | 41.3(34.2–48.3) | 26.4(22.0–30.8) | 25.8(20.0–31.7) | <0.001 | 0.13 | 0.276 |
ARI sex risks subscore Mean (95% CI) | 15.4(11.7–19.0) | 15.0(11.7–18.3) | 19.1(15.7–22.6) | 11.7(8.1–15.4) | 11.5(7.9–15.2) | 14.4(10.6–18.2) | 13.4(9.4–17.3) | 12.0(8.0–16.0) | 14.2(9.8–18.6) | 0.136 | 0.193 | 0.983 |
IDU past 30 days n/N (%) | 20/41(49%) | 1/42(2.4%) | 5/36(14%) | 16/42(38%) | 2/30(6.7%) | 2/29(6.9%) | 16/39(41%) | 2/29(6.9%) | 2/23(8.7%) | <0.001 | 0.716 | 0.669 |