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. Author manuscript; available in PMC: 2014 Jun 2.
Published in final edited form as: Lancet. 2008 Jun 28;371(9631):2192–2200. doi: 10.1016/S0140-6736(08)60954-X

Table 3.

Effects of treatment group assignment on AIDS Risk Behaviors (N=126)

Buprenorphine Naltrexone Placebo
Baseline 3-month 6-month Baseline 3-month 6-month Baseline 3-month 6-month Time effect Medication effect Interaction
n=41 n=42 n=36 n=42 n=30 n=29 n=39 n=29 n=23 p p p
ARI total score Mean (95%CI) 56.5(48.0–64.9) 47.3(41.7–53.0) 53.7(44.1–63.4) 46.4(37.9–54.0) 43.7(36. 7–50.6) 43.1(33. 5–52.7) 57.0(46.7–67.1) 47.4(39.5–55.3) 43.6(34.9–52.4) <0.01 0.138 0.321
ARI drug risks subscore Mean (95% CI) 38.9(32.7–45.1) 23.1(19.3–26.8) 25.0(20.2–29.8) 30.4(24.0–36.8) 22.5(18.3–26.8) 21.8(16.5–27.1) 41.3(34.2–48.3) 26.4(22.0–30.8) 25.8(20.0–31.7) <0.001 0.13 0.276
ARI sex risks subscore Mean (95% CI) 15.4(11.7–19.0) 15.0(11.7–18.3) 19.1(15.7–22.6) 11.7(8.1–15.4) 11.5(7.9–15.2) 14.4(10.6–18.2) 13.4(9.4–17.3) 12.0(8.0–16.0) 14.2(9.8–18.6) 0.136 0.193 0.983
IDU past 30 days n/N (%) 20/41(49%) 1/42(2.4%) 5/36(14%) 16/42(38%) 2/30(6.7%) 2/29(6.9%) 16/39(41%) 2/29(6.9%) 2/23(8.7%) <0.001 0.716 0.669