Figure 4.
ALN-induced differences in average osteon size and lacunae density. (a) Cross sectional area contained in osteons normalized by beam area, osteon density (On.Dn) and average area of osteons (On.Ar) for beams in each of the 3 groups. (b) Section of one beam cross-section illustrating osteons (large arrow) and osteocyte lacunae (smaller arrows); scale bar = 100 µm. (c) Total and osteon osteocyte lacunae areal density (Ot.Lc.Dn). Means ± SD; n = 7 – 10 / group. ANOVA, followed by Tukey HSD: vs. control (VEH), a p<0.05, b p < 0.01