Table 1. Demographic characteristics of patients with blood stream infection or intracranial infection.
| Derivation cohort (n = 342) | Validation cohort (n = 90) | ||||
| Characteristics | blood stream infection (n = 299) | cerebral spinal fluid infection (n = 43) | P value | blood stream infection (n = 77) | cerebral spinal fluid infection (n = 13) |
| Median age (range), year | 1.75 (0.03–17.5) | 0.84 (0.14–11.1) | 0.246 | 1.84 (0.11–16.0) | 1.0 (0.10–10.3) |
| Gender (male/female) | 214/85 | 30/13 | 0.857 | 56/21 | 9–4 |
| Organism | |||||
| ram-negative bacteria | 74 (24.7%) | 12 (27.9%) | 20 (26.0%) | 4 (30.8%) | |
| escherichia coli | 30 | 4 | 12 | 2 | |
| serratia marcescens | 9 | 0 | 2 | 0 | |
| pseudomonas aeruginosa | 6 | 1 | 1 | 1 | |
| salmonella | 5 | 0 | 0 | 0 | |
| pseudomonas maltophilia | 5 | 0 | 1 | 0 | |
| ebsiella pneumoniae | 4 | 4 | 3 | 1 | |
| acinetobacter baumannii | 3 | 0 | 0 | 0 | |
| klebsiella oxytoca | 3 | 1 | 0 | 0 | |
| haemophilus influenzae | 2 | 1 | 0 | 0 | |
| moraxella | 3 | 0 | 0 | 0 | |
| ochrobactrum anthropi | 3 | 0 | 0 | 0 | |
| burkholderia cepacia | 1 | 0 | 1 | 0 | |
| enterobacter cloacae | 0 | 1 | 0 | 0 | |
| Gram-positive bacteria | 225 (75.3%) | 31 (72.1%) | 57 (74.0%) | 9 (69.2%) | |
| coagulase negative staphylococcus | 154 | 18 | 21 | 4 | |
| micrococcus | 18 | 5 | 5 | 2 | |
| corynebacterium | 10 | 0 | 6 | 0 | |
| enterococcus | 8 | 2 | 8 | 0 | |
| streptococcus pneumoniae | 8 | 3 | 4 | 1 | |
| bacillus | 6 | 0 | 1 | 0 | |
| streptococcus mitis | 6 | 1 | 3 | 1 | |
| staphylococcus aureus | 5 | 0 | 4 | 0 | |
| nocardia asteroids | 4 | 1 | 1 | 0 | |
| streptococcus viridans | 3 | 0 | 2 | 0 | |
| streptococcus agalactiae | 1 | 0 | 1 | 0 | |
| streptococcus salivarius | 1 | 1 | 0 | 1 | |
| streptococcus bovis | 1 | 0 | 1 | 0 | |
| underlying diseases | |||||
| pneumonia | 152 | 10 | 29 | 3 | |
| sepsis | 85 | 0 | 18 | 0 | |
| enteritis | 16 | 0 | 9 | 0 | |
| bronchiolitis | 12 | 0 | 7 | 0 | |
| upper respiratory infection | 8 | 0 | 2 | 0 | |
| diarrhea | 8 | 0 | 4 | 0 | |
| tonsillitis | 8 | 0 | 4 | 0 | |
| bronchitis | 6 | 0 | 3 | 0 | |
| jaundice | 4 | 0 | 1 | 0 | |
| traumatic subdural haemorrhage | 0 | 2 | 0 | 0 | |
| hydrocephaly | 0 | 2 | 0 | 0 | |
| cerebral contusion | 0 | 2 | 0 | 0 | |
| skull fracture | 0 | 1 | 0 | 1 | |
| omphalitis | 0 | 3 | 0 | 0 | |
| encephalitis | 0 | 15 | 0 | 6 | |
| purulent meningitis | 0 | 8 | 0 | 3 | |