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. 2014 Jun 2;9(6):e98460. doi: 10.1371/journal.pone.0098460

Figure 4. Antibody-dependent cellular inhibition activity with affinity purified antibodies.

Figure 4

In vitro parasite specific growth inhibition (SGI) in the presence of human monocytes and human affinity-purified anti-OR or anti-SR IgG or murine anti-SE36 IgG at 0.3 mg/ml. A pool of polyclonal immune African IgG from individuals living in endemic areas was used as positive control at a final concentration of 2 mg/ml. IgG purified from malaria naïve human sera was used as negative control and included in the formula for SGI calculation as described in Materials and Methods. Mean values from duplicate ELISA with individual data points are shown.