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. 2014 Jun 2;9(6):e98330. doi: 10.1371/journal.pone.0098330

Figure 3. Methylation patterns of known germ cell markers (A–D) and significant DMRs for both cell lines (E, F).

Figure 3

Dots depict individual CpGs and black boxes denote DMRs identified by DMRforPairs. Percentages below indicate average CG density in the plotted regions (calculated using the Repitools R package, gcContentCalc function (http://www.bioconductor.org/)). (A) SOX2 [44%], (B) SOX17 [46%], (C) OCT3/4 (POU5F1), [52%] (D) NANOG, [44%] (E) miR-371/2/3 cluster, [49%] (F) GATA4 [53%].