Table 5.
Correlation between test outcomes and EDSS
| |
A |
|
B |
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Total score | FS | VIS | BS | PYR | cer | SENS | B&B | CER | |
| |
Median |
3.0 |
0 |
12 |
7 |
3 |
4 |
2 |
9 |
5 |
| |
Min |
0.0 |
1 |
9 |
10 |
6 |
8 |
8 |
7 |
9 |
| |
Max |
6.0 |
2 |
1 |
5 |
8 |
6 |
10 |
5 |
8 |
| |
|
|
3+ |
|
|
5 |
4 |
2 |
1 |
|
| T25FW* |
Rho |
0.694 |
Rho |
0.492 |
0.304 |
0.161 |
0.394 |
-0.081 |
0.397 |
0.539 |
| |
P
|
<0.001 |
P
|
0.023 |
0.180 |
0.485 |
0.077 |
0.727 |
0.075 |
0.012 |
| SMSW Average speed |
Rho |
-0.701 |
Rho |
0.060 |
-0.516 |
-0.634 |
-0.355 |
-0.126 |
-0.204 |
-0.430 |
| |
P
|
<0.001 |
P
|
0.789 |
0.014 |
0.002 |
0.105 |
0.578 |
0.362 |
0.046 |
| SMSW Speed deviation |
Rho |
0.276 |
Rho |
0.286 |
0.369 |
0.024 |
0.122 |
-0.453 |
0.155 |
0.291 |
| |
P
|
0.213 |
P
|
0.198 |
0.091 |
0.917 |
0.588 |
0.034 |
0.491 |
0.189 |
| SMSW Derived T25FW |
Rho |
0.676 |
Rho |
-0.060 |
0.516 |
0.639 |
0.327 |
0.090 |
0.204 |
0.428 |
| |
P
|
0.001 |
P
|
0.789 |
0.014 |
0.001 |
0.137 |
0.690 |
0.362 |
0.047 |
| SMSW 3D direction deviation |
Rho |
0.439 |
Rho |
0.086 |
0.411 |
0.196 |
0.074 |
0.048 |
-0.099 |
0.317 |
| |
P
|
0.041 |
P
|
0.705 |
0.057 |
0.382 |
0.743 |
0.834 |
0.662 |
0.151 |
| SMSW Left/right deviation |
Rho |
0.429 |
Rho |
0.072 |
0.392 |
0.191 |
0.033 |
0.007 |
-0.125 |
0.317 |
| |
P
|
0.046 |
P
|
0.750 |
0.071 |
0.395 |
0.884 |
0.974 |
0.579 |
0.151 |
| SMSW Up/down deviation |
Rho |
-0.134 |
Rho |
-0.122 |
-0.301 |
-0.181 |
-0.264 |
-0.246 |
0.056 |
-0.397 |
| P | 0.551 | P | 0.590 | 0.173 | 0.421 | 0.236 | 0.269 | 0.806 | 0.067 | |
P values are given in italic; correlation coefficients from tests with significant results are given in bold. A) Overview of EDSS distribution and results from a Spearman’s Rho analysis compared to the results of investigated measures and standard T25FW results. B) Detailed overview of FS distribution and Spearman’s Rho analysis results. *) The T25FW analysis is based on data from 21 MS patients and 14 HC.
Abbreviations:T25FW Timed 25-Foot Walk, EDSS Expanded Disability Status Scale, FS EDSS functional system score, VIS visual system score, BS brainstem score, PYR pyramidal tract score, cer cerebellar score, SENS sensory system score, B&B bowel and bladder score, CER cerebral score.