Table 1.

Characteristics of subjects stratified by presence of anxiety and/or depression status

	Total	Anxiety and/or Depression status		P value
		Yes (n = 95)	No (n = 264)
Age, mean ± SD	65.64 ± 7.60	64.25 ± 7.84	66.14 ± 7.47	0.038
Gender, n (male/female)	327/32	77/18	250/14	<0.001
Pack-year history, mean ± SD	33.65 ± 18.37	32.46 ± 20.28	34.08 ± 17.66	0.463
Duration of COPD, years, mean ± SD	6.69 ± 5.32	6.77 ± 6.19	6.66 ± 4.98	0.859
CAT, mean ± SD	16.42 ± 7.20	20.17 ± 6.50	15.06 ± 6.97	<0.001
mMRC, mean ± SD	1.53 ± 0.85	1.86 ± 0.86	1.42 ± 0.82	<0.001
BCKQ, mean ± SD	30.36 ± 9.59	26.85 ± 9.16	31.63 ± 9.45	<0.001
HAD-A, mean ± SD	3.54 ± 3.74	7.87 ± 3.69	1.98 ± 2.24	<0.001
HAD-D, mean ± SD	4.17 ± 3.76	8.97 ± 2.69	2.45 ± 2.31	<0.001
FEV1, L, mean ± SD	1.11 ± 0.44	1.04 ± 0.41	1.14 ± 0.45	0.062
FEV1% predict, mean ± SD	42.88 ± 25.56	39.12 ± 14.77	44.23 ± 28.36	0.094
Post FEV1, L, mean ± SD	1.22 ± 0.47	1.16 ± 0.47	1.24 ± 0.46	0.133
Post FEV1% predict, mean ± SD	46.77 ± 25.88	43.37 ± 116.19	48.00 ± 28.50	0.135
6MWD, m, mean ± SD	429.64 ± 115.39	431.38 ± 124.34	429.01 ± 112.24	0.864
Primary school, n (%)	106 (29.53%)	27 (28.42%)	79 (29.92%)	0.783
Junior high school, n (%)	129 (35.93%)	42 (44.21%)	87 (32.95%)	0.050
Senior high school, n (%)	59 (16.43%)	14 (14.74%)	45 (31.78%)	0.603
Junior college or above, n (%)	55 (15.32%)	8 (8.42%)	47 (17.80%)	0.029
Other, n (%)	10 (2.79%)	4 (4.21%)	6 (2.27%)	0.301

Abbreviations: CAT COPD Assessment Test, mMRC modified Medical Research Council, BCKQ Bristol COPD Knowledge Questionnaire, HAD Hospital Anxiety and Depressive Scale, HAD-A HAD-anxiety, HAD-D HAD-Depression, FEV1 Forced Expiratory Volume in 1 Second, postFEV1 post-bronchodilator FEV1, 6MWD Six-Minute Walking Distance Test; Definition of Anxiety and/or Depression Status: HAS-A ≥8 and/or HAD-D score ≥8.