Table 2.
List of gene sets commonly regulated by PTPRJ and PTPN11 based on gene expression
| Gene set name | K | k | k/K* | P value |
|---|---|---|---|---|
| KEGG_Pathways_in_cancer | 328 | 10 | 0.0305 | 6.86 × 10-7 |
| KEGG_Focal_adhesion | 201 | 8 | 0.0398 | 1.70 × 10-6 |
| KEGG_ERBB_Signaling_pathway | 87 | 6 | 0.069 | 1.81 × 10-6 |
| KEGG_Cytokine_cytokine_receptor_interaction | 267 | 8 | 0.03 | 1.42 × 10-5 |
| KEGG_Neurotrophin_signaling_pathway | 126 | 6 | 0.0476 | 1.57 × 10-5 |
| KEGG_Adherens_junction | 75 | 5 | 0.0667 | 1.76 × 10-5 |
| KEGG_Prostate_cancer | 89 | 5 | 0.0562 | 4.06 × 10-5 |
| KEGG_JAK_Stat_signaling_pathway | 155 | 6 | 0.0387 | 5.11 × 10-5 |
| KEGG_Endometrial_cancer | 52 | 4 | 0.0769 | 7.76 × 10-5 |
| KEGG_Non_small_cell_lung_cancer | 54 | 4 | 0.0741 | 9.01 × 10-5 |
| KEGG_T_Cell_receptor_signaling_pathway | 108 | 5 | 0.0463 | 1.03 × 10-4 |
| KEGG_Endocytosis | 183 | 6 | 0.0328 | 1.29 × 10-4 |
| KEGG_Chemokine_signaling_pathway | 190 | 6 | 0.0316 | 1.59 × 10-4 |
| KEGG_Glioma | 65 | 4 | 0.0615 | 1.87 × 10-4 |
| KEGG_Renal_cell_carcinoma | 70 | 4 | 0.0571 | 2.49 × 10-4 |
| KEGG_Thyroid_cancer | 29 | 3 | 0.1034 | 2.81 × 10-4 |
| KEGG_VEGF_signaling_pathway | 76 | 4 | 0.0526 | 3.42 × 10-4 |
| KEGG_Leukocyte_transendothelial_migration | 118 | 4 | 0.0339 | 1.80 × 10-4 |
| KEGG_Acute_myeloid_leukemia | 60 | 3 | 0.05 | 2.40 × 10-3 |
*k/K is the ratio between the number of genes in overlap (k) and the number of genes in gene set (K).